The collection consists of correspondence, diaries, invitations, circulars, news clips, manuscripts, Saugrain family baptismal records, land surveys, deeds, obituaries, genealogical information, and the Civil War papers of John Waddell, husband of Dr. Saugrain's granddaughter, Rosalie Genevieve Saugrain. Saugrain's letters include information on his 1788 expedition through the Ohio Valley, financed by the Count of Galvey, Viceroy of Mexico, with detailed accounts of his escape from an Indian attack along the river. Saugrain's diary, along with a translation, also describes the expedition and Indian attack. There are a number of letters (Box 1/Folder 2) written to Dr. Saugrain from his mother in Paris that tell of post-revolutionary events in France including news of Napoleon's return from Egypt. The letters also express Mother Saugrain's concern over the health of Antoine's children and family news. There are several letters (Box 1/Folders 2-5) written by Madame Guillotine, with whom Dr. Saugrain's family was acquainted. The collection contains the marriage certificate of Antoine Saugrain and Genevieve Michau and the commission appointing Antoine Saugrain as surgeon's mate at Fort Bellefontaine. There are land documents relating to Saugrain family property and land claims. A folder of baptismal records of members of the Saugrain family is arranged separately and is located in Box 2. The papers of John Waddell, husband of Rosalie Saugrain, contain his parole and loyalty oath administered after his release from a Union prison camp at the end of the Civil War; a business card–sized sketch of Johnson's Island Prison in Sandusky, Ohio; an ex-Confederate soldier's pension application; and correspondence with family, circa 1925 (Box 2/Folder 4). The remainder of the collection consists of genealogical information on the Saugrain-Michau families along with an obituary and biographical sketch of the life of Henry Von Puhl, son-in-law of Dr. Saugrain. Addition information on the family of Henry Von Puhl can be found in the Von Puhl Family Papers.