The Kayla Vaughan Image Collection contains photographs and posters documenting Vaughan’s personal life and political activism.

Photographs related to Vaughan’s involvement in lesbian and feminist circles show candid shots of Vaughan and other women, including her girlfriend, Diana Campbell. Many of the photographs were taken at 6188 Westminster, a feminist collective of students and recent graduates from Washington University. These photos include the 1st and 2nd annual Folkhera Ball, as well as other parties. Several shots show groups on Washington University’s campus. Additional images show “Lesbian Love” graffiti, including graffiti near a Playboy bunny image most likely at the Playboy Club on Lindell. One exterior view shows 4367 Westminster, where Vaughan lived as part of a lesbian collective.

Additional photographs show Vaughan and husband Dennis Roach playing in the snow in Tower Grove Park after the 1982 blizzard.

The collection also includes multiple copies of two posters. One poster advertises events at Grace Methodist Church to celebrate International Women’s Day on March 8, 1980. The second poster urges voters to reject Amendment 23, a 1978 proposed amendment that would have added an anti-union "right to work" provision to the Missouri state constitution. The poster was probably designed by local lesbian feminist activist Barb Goedde and/or Clare Kinberg. It features an image taken from the archives of the University of Missouri-St. Louis of a racially mixed group of women marching in a 1933 garment workers' strike in downtown St. Louis. The imagery on the poster was meant to be a reminder of the epic workers' struggles of the Great Depression era and to connect the women's community to a tradition of multiracial organizing and labor activism.