The collection contains two items that are clearly from the Woodruff family, namely, the bound school notebook of F.C. Woodruff and the Missouri Historical Society family history form, filled out by Frederick Eno Woodruff. However, the remainder of the collection is a disparate assortment of documents that cannot be readily associated with the Woodruff family. Other surnames that appear in the collection more than once are Fauntleroy, Schrage, and Uhlich. The bulk of the collection relates to St. Louis, and includes receipts, newspaper clippings, calling cards, business cards, printed programs and invitations, mostly relating to events at St. Louis–area schools and churches, and advertising material for St. Louis–area businesses. Several items in the collection relate to art.